Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | CDK7 | P50613 | 3/20 | 0.40 |
| ▸ | CDK9 | P50750 | 3/20 | 0.40 |
| ▸ | CCNH | P51946 | 3/20 | 0.40 |
| ▸ | CCNK | O75909 | 2/20 | 0.40 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.40 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051591 | 0.87 | ITGB3 (0.46) | PPARAPPARDCASRPPARGMAPK8 | |
| SCHEMBL7469681 | 0.85 | NOTUM (0.43) | NOTUMDRD2DRD3 | |
| SCHEMBL7470666 | 0.85 | OPRK1 (0.49) | CCNT1CCNA2CDK2CDK7CDK9 | |
| SCHEMBL7463214 | 0.82 | CASR (0.54) | PPARACNR1CASRDRD2DRD3 | |
| SCHEMBL7053339 | 0.82 | CASR (0.54) | PPARACNR1CASRDRD2DRD3 | |
| SCHEMBL6498986 | 0.81 | KDM4E (0.54) | PPARACCNKCDK12PPARDCASR | |
| SCHEMBL6497606 | 0.81 | KDM4E (0.54) | PPARACCNKCDK12PPARDCASR | |
| SCHEMBL7468836 | 0.80 | EPHX2 (0.41) | PPARANOTUMEPHX2CCNT1CCNA2 | |
| SCHEMBL7467132 | 0.79 | CASR (0.51) | PPARACASRDRD2DRD3 | |
| SCHEMBL7461777 | 0.78 | ITGB3 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |