Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CCNH | P51946 | 1/20 | 0.40 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466048 | 0.91 | OPRK1 (0.51) | OPRK1CASP3MAPTCCNT1CCNK | |
| SCHEMBL7050644 | 0.89 | OPRK1 (0.49) | OPRK1MAPTTSHRKDM4EGAA | |
| SCHEMBL7466392 | 0.86 | OPRK1 (0.47) | OPRK1MAPTMAPK1HTTTSHR | |
| SCHEMBL7463196 | 0.85 | PPARA (0.41) | DGAT1CCNT1CCNKCCNA2CDK2 | |
| SCHEMBL7054705 | 0.84 | OPRK1 (0.49) | OPRK1MAPTMAPK1HTTCCNK | |
| SCHEMBL7468246 | 0.84 | OPRK1 (0.49) | OPRK1MAPTMAPK1HTTCCNK | |
| SCHEMBL7470661 | 0.80 | OPRK1 (0.42) | OPRK1CASP3MAPTMAPK1HTT | |
| SCHEMBL7463266 | 0.79 | PRKD3 (0.47) | MAPTMAPK1HTTTSHRKDM4E | |
| SCHEMBL382149 | 0.78 | OPRK1 (0.51) | OPRK1MAPTMAPK1HTTDGAT1 | |
| SCHEMBL383015 | 0.78 | OPRK1 (0.51) | OPRK1MAPTMAPK1HTTDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |