Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111609 | 0.88 | KCNN4 (0.38) | ALDH1A1MAPTHSD17B10L3MBTL1CYP2B6 | |
| SCHEMBL31230458 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MAPTHSD17B10L3MBTL1CYP2B6 | |
| SCHEMBL2697747 | 0.71 | CYP2B6 (0.53) | ALDH1A1MAPTHSD17B10L3MBTL1CYP2B6 | |
| SCHEMBL7470908 | 0.71 | CYP2B6 (0.47) | ALDH1A1CYP2B6MEN1KMT2AHTT | |
| SCHEMBL8092347 | 0.68 | HTT (0.41) | ALDH1A1MAPTHSD17B10L3MBTL1CYP2B6 | |
| SCHEMBL1829012 | 0.68 | HTT (0.49) | ALDH1A1MAPTHSD17B10L3MBTL1MEN1 | |
| SCHEMBL2695770 | 0.66 | CYP2B6 (0.50) | ALDH1A1MAPTHSD17B10L3MBTL1CYP2B6 | |
| SCHEMBL1272614 | 0.65 | ALDH1A1 (0.37) | ALDH1A1MAPTHSD17B10L3MBTL1MEN1 | |
| SCHEMBL7422477 | 0.65 | POLB (0.45) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27603655 | 0.64 | L3MBTL1 (0.46) | MAPTL3MBTL1ACHEKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |