SCHEMBL7463329

SCHEMBL7463329

CC(Nc1ccccc1)C(=O)OC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
TDP1 Q9NUW8 3/20 0.44
ALDH1A1 P00352 3/20 0.43
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
RECQL P46063 1/20 0.43
GAA P10253 1/20 0.42
BTN3A1 O00481 2/20 0.42
POLB P06746 1/20 0.42
KDM4E B2RXH2 1/20 0.40
MAPK1 P28482 1/20 0.40
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7463341 1.00 MAPT (0.50) MAPTTDP1ALDH1A1KMT2AMEN1
SCHEMBL7990373 1.00 MAPT (0.50) MAPTTDP1ALDH1A1KMT2AMEN1
Hydrochloric Acid SCHEMBL3881057 0.98 MAPT (0.49) MAPTTDP1ALDH1A1KMT2AMEN1
SCHEMBL21952787 0.89 MAPT (0.51) MAPTTDP1ALDH1A1KMT2AMEN1
SCHEMBL4183889 0.85 TDP1 (0.51) MAPTTDP1ALDH1A1KMT2AMEN1
SCHEMBL4187563 0.85 TDP1 (0.51) MAPTTDP1ALDH1A1KMT2AMEN1
SCHEMBL9297119 0.84 MAPT (0.42) MAPTTDP1KMT2AGAAMAPK1
SCHEMBL4180831 0.83 FPR2 (0.43) MAPTTDP1ALDH1A1KMT2AMEN1
SCHEMBL4821613 0.83 ADRB2 (0.40) MAPTTDP1ALDH1A1KMT2AMEN1
SCHEMBL4177243 0.83 FPR2 (0.43) MAPTTDP1ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6498004-B1 FRAGMENTABLE TWO-ELECTRON DONOR COMPOUNDS THAT ARE ATTACHED TO A PROTECTIVE GROUP WHEREIN SUCH PROTECTIVE GROUP IS ELIMINATED DURING DEVELOPMENT TO GIVE THE FRAGMENTABLE ELECTRON DONOR; WITHOUT AN INCREASE IN FOG EASTMAN KODAK COMPANY 2002-12-24 US disclosed
CN-1362640-A Silver-halides photo-sensitive emulsion layer with reinforced photographic photosensibility EASTMAN KODAK CO (US) 2002-08-07 CN disclosed
EP-1220024-A2 Silver halide photographic element EASTMAN KODAK COMPANY (US) 2002-07-03 EP disclosed