Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPR3 | P17342 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183889 | 1.00 | TDP1 (0.51) | TDP1XBP1CA12CA1MMP8 | |
| SCHEMBL4821613 | 0.85 | ADRB2 (0.40) | TDP1XBP1CA12CA1MAPT | |
| SCHEMBL4177243 | 0.85 | FPR2 (0.43) | TDP1XBP1CA12MAPTMAPK1 | |
| SCHEMBL4180831 | 0.85 | FPR2 (0.43) | TDP1XBP1CA12MAPTMAPK1 | |
| SCHEMBL7463329 | 0.85 | MAPT (0.50) | TDP1MAPTKDM4EMAPK1ATM | |
| SCHEMBL7990373 | 0.85 | MAPT (0.50) | TDP1MAPTKDM4EMAPK1ATM | |
| SCHEMBL7463341 | 0.85 | MAPT (0.50) | TDP1MAPTKDM4EMAPK1ATM | |
| Hydrochloric Acid SCHEMBL4822641 | 0.84 | ADRB2 (0.40) | TDP1XBP1CA12CA1MAPT | |
| SCHEMBL8339856 | 0.84 | MAPT (0.53) | MAPTALDH1A1KMT2ANPSR1LMNA | |
| Hydrochloric Acid SCHEMBL3881057 | 0.83 | MAPT (0.49) | TDP1MAPTKDM4EMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722919-B2 | Process for production of mono-substituted alkylated compound using aldimine or derivative thereof | NAGASE & CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20090054679-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | NAGASE & CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1930315-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | NAGASE & COMPANY, LTD. (JP) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054679-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | AADAT, BCAT2, BCAT1 | TDP1 3959/4885XBP1 4377/4885CA12 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.