Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472833 | 0.84 | MAPT (0.48) | TSHRGAACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7472667 | 0.82 | TP53 (0.42) | TP53RXFP1MAPTSMN1; SMN2POLB | |
| SCHEMBL7467388 | 0.82 | PSEN1 (0.42) | TSHRHPGDHDAC8ALDH1A1HSD17B10 | |
| SCHEMBL7468006 | 0.80 | MAPT (0.46) | TSHRGAACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7465212 | 0.80 | PPARG (0.43) | RXFP1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7463375 | 0.80 | PSEN1 (0.39) | KMT2ANPSR1SMN1; SMN2MCL1 | |
| SCHEMBL7563746 | 0.80 | MAPT (0.49) | TP53RXFP1MAPTMEN1KMT2A | |
| SCHEMBL7461911 | 0.78 | MAPT (0.44) | GAATP53MAPTMEN1KMT2A | |
| SCHEMBL7472701 | 0.78 | PSEN1 (0.42) | TSHRNPSR1HDAC8ALDH1A1SMN1; SMN2 | |
| SCHEMBL7468103 | 0.78 | GAA (0.44) | GAATP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |