Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 12/20 | 0.42 |
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472833 | 0.86 | MAPT (0.48) | TP53MAPTPOLBSMN1; SMN2 | |
| SCHEMBL7461911 | 0.83 | MAPT (0.44) | TP53MAPTPOLBSMN1; SMN2 | |
| SCHEMBL7463377 | 0.82 | TSHR (0.42) | TP53MAPTRXFP1POLBSMN1; SMN2 | |
| SCHEMBL7468006 | 0.82 | MAPT (0.46) | TP53MAPTPOLBSMN1; SMN2 | |
| SCHEMBL7563746 | 0.81 | MAPT (0.49) | TP53MAPTRXFP1POLB | |
| SCHEMBL7467388 | 0.80 | PSEN1 (0.42) | — | |
| SCHEMBL7465395 | 0.80 | TP53 (0.51) | TP53MAPTPOLBSMN1; SMN2 | |
| SCHEMBL7468103 | 0.80 | GAA (0.44) | TP53MAPTNAMPTSMN1; SMN2 | |
| SCHEMBL7472664 | 0.80 | GAA (0.38) | MAPTPOLB | |
| SCHEMBL7457228 | 0.79 | HDAC6 (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |