Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469787 | 0.92 | HTT (0.48) | PRKCQHTTMAPTDNMT1DNMT3A | |
| SCHEMBL7468943 | 0.91 | MAPK1 (0.46) | PRKCQMAPK1EGFRHTTLMNA | |
| SCHEMBL7465055 | 0.86 | HTR6 (0.55) | MAPK1EGFRHTTLMNAAPP | |
| SCHEMBL7466158 | 0.86 | HTR6 (0.55) | MAPK1EGFRHTTLMNAAPP | |
| SCHEMBL7458966 | 0.85 | MAPK1 (0.47) | MAPK1EGFRHTTLMNAAPP | |
| SCHEMBL7471194 | 0.84 | MAPK1 (0.48) | MAPK1EGFRHTTLMNAAPP | |
| SCHEMBL7470615 | 0.83 | HTT (0.50) | MAPK1HTTLMNAMAPTDNMT1 | |
| SCHEMBL7470361 | 0.83 | HTT (0.45) | PRKCQMAPK1HTTSMN1; SMN2AURKA | |
| SCHEMBL7467064 | 0.83 | HTR6 (0.52) | MAPK1EGFRHTTLMNAAPP | |
| SCHEMBL7465454 | 0.83 | ACHE (0.47) | MAPK1EGFRHTTLMNAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |