Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464749 | 0.94 | MCHR1 (0.61) | MCHR1DRD2KCNH2CCR2HDAC3 | |
| SCHEMBL7459547 | 0.89 | MCHR1 (0.65) | MCHR1DRD2CCR2SLC6A2SLC6A4 | |
| SCHEMBL7464781 | 0.86 | MCHR1 (0.73) | MCHR1SIGMAR1DRD2KCNH2CCR2 | |
| SCHEMBL7470119 | 0.84 | MCHR1 (0.68) | MCHR1SIGMAR1DRD2CCR2SLC6A2 | |
| SCHEMBL7466997 | 0.83 | MCHR1 (0.61) | MCHR1CCR2HDAC3HDAC1ADRA1A | |
| SCHEMBL7467493 | 0.83 | MCHR1 (0.61) | MCHR1HTR4HDAC3HDAC1ADRA1A | |
| SCHEMBL7462229 | 0.83 | MCHR1 (0.62) | MCHR1DRD2SLC6A2SLC6A4DRD3 | |
| SCHEMBL7463521 | 0.83 | MCHR1 (0.66) | MCHR1ADRA1ACCR1 | |
| SCHEMBL7462164 | 0.80 | MCHR1 (0.62) | MCHR1HTR4DRD2CCR2DRD3 | |
| SCHEMBL7462536 | 0.80 | MCHR1 (0.58) | MCHR1SLC6A2SLC6A4DRD3CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |