Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 4/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 4/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467493 | 0.87 | MCHR1 (0.61) | MCHR1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7464717 | 0.85 | MCHR1 (0.64) | MCHR1CCR1KCNA3CCR3DRD3 | |
| SCHEMBL7464749 | 0.84 | MCHR1 (0.61) | MCHR1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7463548 | 0.83 | MCHR1 (0.60) | MCHR1HDAC1HDAC3CCR1CCR2 | |
| SCHEMBL7463521 | 0.83 | MCHR1 (0.66) | MCHR1CCR1KCNA3CCR3HTR7 | |
| SCHEMBL7465464 | 0.83 | MCHR1 (0.63) | MCHR1CCR1KCNA3CCR3DRD3 | |
| SCHEMBL7464781 | 0.83 | MCHR1 (0.73) | MCHR1CCR1KCNA3CCR3CCR2 | |
| SCHEMBL7459547 | 0.83 | MCHR1 (0.65) | MCHR1CCR2DRD3ADRA1A | |
| SCHEMBL7462164 | 0.82 | MCHR1 (0.62) | MCHR1CCR2DRD3 | |
| SCHEMBL7462229 | 0.81 | MCHR1 (0.62) | MCHR1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |