Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 16/20 | 0.32 |
| ▸ | F11 | P03951 | 2/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | ABL2 | P42684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468685 | 0.88 | ADH1A (0.32) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL7469597 | 0.84 | PYGL (0.32) | F11ADH1AKITFLT1FLT4 | |
| SCHEMBL7460763 | 0.83 | KDM4E (0.37) | — | |
| SCHEMBL7465517 | 0.83 | KDM4E (0.36) | — | |
| SCHEMBL7463553 | 0.83 | KDM4E (0.36) | — | |
| SCHEMBL6627433 | 0.83 | MAPT (0.38) | — | |
| SCHEMBL7464956 | 0.83 | KDM4E (0.35) | — | |
| SCHEMBL7468222 | 0.83 | NPC1 (0.37) | LEF1 | |
| SCHEMBL6520370 | 0.82 | ADH1A (0.48) | LEF1RORCF11ADH1AKIT | |
| SCHEMBL6520374 | 0.82 | ADH1A (0.48) | LEF1RORCF11ADH1AKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656360-B1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5629430-A | ANTICARCINOGENIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0656360-A1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |