Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.54 |
| ▸ | FPR2 | P25090 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27544570 | 0.85 | ANPEP (0.51) | ANPEPFPR2 | |
| SCHEMBL7419417 | 0.85 | ANPEP (0.49) | ANPEPFPR2 | |
| SCHEMBL7416181 | 0.81 | FPR2 (0.62) | ANPEPFPR2 | |
| SCHEMBL7419891 | 0.78 | MAPT (0.53) | ANPEPNPC1POLB | |
| SCHEMBL7411160 | 0.76 | FPR2 (0.57) | ANPEPFPR2POLB | |
| SCHEMBL1109398 | 0.75 | HDAC1 (0.49) | — | |
| SCHEMBL7415730 | 0.75 | NPC1 (0.54) | FPR2NPC1POLB | |
| SCHEMBL8103174 | 0.75 | FPR2 (0.49) | ANPEPFPR2NPC1POLB | |
| SCHEMBL19201543 | 0.75 | FPR2 (0.76) | ANPEPFPR2 | |
| SCHEMBL18053826 | 0.74 | PTPN7 (0.54) | NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218389-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS; SKIN DISORDERS; OCULAR DISORDERS; INFLAMMATION AND GUM DISEASES, MULTIPLE SCLEROSIS, CACHEXIA, PREVENTING LOOSENING OF PROSTHETIC DEVICES | THE PROCTER & GAMBLE CO. | 2001-04-17 | — | — | US | disclosed |
| EP-1009737-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999006340-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |