Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411160 | 0.89 | FPR2 (0.57) | FPR2MAPTANPEPMEN1KMT2A | |
| SCHEMBL7419891 | 0.83 | MAPT (0.53) | MAPTANPEPMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5851828 | 0.77 | CA12 (0.62) | MAPTMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL20335078 | 0.76 | FPR2 (0.74) | FPR2MAPTMEN1KMT2AATM | |
| SCHEMBL20335080 | 0.76 | FPR2 (0.74) | FPR2MAPTMEN1KMT2AATM | |
| SCHEMBL1109365 | 0.75 | HDAC1 (0.50) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7463584 | 0.75 | ANPEP (0.54) | FPR2ANPEPPOLBNPC1 | |
| SCHEMBL6790850 | 0.74 | TDP1 (0.61) | MAPTSMN1; SMN2TDP1RAB9APOLB | |
| SCHEMBL10192190 | 0.74 | SMN1; SMN2 (0.76) | FPR2MAPTMEN1KMT2ASMN1; SMN2 | |
| Benzene SCHEMBL9395088 | 0.74 | CA12 (0.58) | MAPTMEN1KMT2ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009737-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999006340-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |