Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.52 |
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | HTR1A | P08908 | 9/20 | 0.51 |
| ▸ | HTR7 | P34969 | 5/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9049243 | 0.95 | HTR1D (0.49) | OPRM1OPRK1OPRL1SLC6A4DRD2 | |
| SCHEMBL8111835 | 0.89 | OPRM1 (0.57) | OPRM1OPRK1OPRL1SLC6A4DRD2 | |
| SCHEMBL7459131 | 0.89 | CYP1A2 (0.56) | OPRM1OPRK1OPRL1SLC6A4DRD2 | |
| SCHEMBL7460288 | 0.89 | OPRM1 (0.56) | OPRM1OPRK1OPRL1SLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL7009951 | 0.89 | OPRM1 (0.56) | OPRM1OPRK1OPRL1SLC6A4DRD2 | |
| SCHEMBL7459744 | 0.87 | SLC6A4 (0.54) | SLC6A4DRD2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9050891 | 0.86 | ADRA1D (0.55) | SLC6A4DRD2HTR7HTR2AADRA1D | |
| Oxalic Acid SCHEMBL9048457 | 0.84 | HTR1D (0.41) | OPRM1OPRK1OPRL1DRD2HTR1A | |
| Oxalic Acid SCHEMBL9046836 | 0.83 | SLC6A4 (0.51) | SLC6A4DRD2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9048755 | 0.83 | OPRM1 (0.59) | OPRM1OPRK1OPRL1SLC6A4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708102-B1 | 5-HT1F agonists for the treatment of migraine | LILLY CO ELI (US) | 2002-12-11 | — | — | EP | disclosed |
| EP-0708102-A1 | 5-HT1F agonists for the treatment of migraine | ELI LILLY AND COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |