Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 3/20 | 0.43 |
| ▸ | CCR3 | P51677 | 3/20 | 0.43 |
| ▸ | USP5 | P45974 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 5/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462127 | 0.88 | MCHR1 (0.56) | MCHR1MEN1KMT2ACCR1CCR3 | |
| SCHEMBL7465497 | 0.87 | MCHR1 (0.59) | MCHR1KMT2ACCR1CCR3HTR7 | |
| SCHEMBL7460992 | 0.84 | MCHR1 (0.60) | MCHR1CCR1CCR3USP5HTR7 | |
| SCHEMBL7462324 | 0.81 | MCHR1 (0.57) | MCHR1KMT2AUSP5HTR7DRD3 | |
| SCHEMBL7463353 | 0.81 | MCHR1 (0.59) | MCHR1MEN1KMT2AL3MBTL1CCR1 | |
| SCHEMBL7461314 | 0.81 | MCHR1 (0.61) | MCHR1CCR1CCR3HTR7DRD3 | |
| SCHEMBL7469453 | 0.79 | MCHR1 (0.59) | MCHR1CCR1CCR3HTR7ADRA1D | |
| SCHEMBL7464540 | 0.79 | MCHR1 (0.59) | MCHR1CCR1CCR3HTR7DRD2 | |
| SCHEMBL7461973 | 0.79 | MCHR1 (0.58) | MCHR1CCR1CCR3DRD2 | |
| SCHEMBL7470937 | 0.79 | MCHR1 (0.58) | MCHR1USP5HTR7DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |