Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.60 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | USP5 | P45974 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461314 | 0.91 | MCHR1 (0.61) | MCHR1CCR2DRD2DRD3SIGMAR1 | |
| SCHEMBL7462324 | 0.90 | MCHR1 (0.57) | MCHR1CCR2DRD2DRD3SIGMAR1 | |
| SCHEMBL7464540 | 0.89 | MCHR1 (0.59) | MCHR1DRD2SIGMAR1HTR7CCR1 | |
| SCHEMBL7461973 | 0.89 | MCHR1 (0.58) | MCHR1DRD2SIGMAR1CCR1CCR3 | |
| Hydrochloric Acid SCHEMBL7466687 | 0.88 | MCHR1 (0.59) | MCHR1DRD2SIGMAR1HTR7 | |
| SCHEMBL7464781 | 0.86 | MCHR1 (0.73) | MCHR1CCR2DRD2SIGMAR1USP5 | |
| SCHEMBL7466759 | 0.85 | MCHR1 (0.66) | MCHR1 | |
| SCHEMBL7470119 | 0.85 | MCHR1 (0.68) | MCHR1CCR2DRD2DRD3SIGMAR1 | |
| SCHEMBL7470937 | 0.85 | MCHR1 (0.58) | MCHR1CCR2DRD2SIGMAR1USP5 | |
| SCHEMBL7460592 | 0.84 | MCHR1 (0.62) | MCHR1DRD2SIGMAR1HTR7SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |