Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459851 | 0.91 | GLA (0.56) | MCHR1ALDH1A1MAPTTSHRLMNA | |
| Hydrochloric Acid SCHEMBL7456232 | 0.91 | GLA (0.55) | MCHR1ALDH1A1MAPTTSHRLMNA | |
| SCHEMBL7463755 | 0.87 | MCHR1 (0.57) | MCHR1KMT2ADRD2DRD3CCR1 | |
| SCHEMBL7462127 | 0.84 | MCHR1 (0.56) | MCHR1TSHRKMT2ADRD2DRD3 | |
| SCHEMBL7461314 | 0.82 | MCHR1 (0.61) | MCHR1DRD2DRD3CCR1HTR7 | |
| SCHEMBL7460992 | 0.82 | MCHR1 (0.60) | MCHR1TSHRDRD2DRD3CCR1 | |
| SCHEMBL7469453 | 0.81 | MCHR1 (0.59) | MCHR1CCR1HTR7CCR3 | |
| SCHEMBL7464540 | 0.81 | MCHR1 (0.59) | MCHR1DRD2CCR1HTR7CCR3 | |
| SCHEMBL7470937 | 0.80 | MCHR1 (0.58) | MCHR1DRD2HTR7 | |
| SCHEMBL7461973 | 0.80 | MCHR1 (0.58) | MCHR1DRD2CCR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |