Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.58 |
| ▸ | CCR3 | P51677 | 4/20 | 0.47 |
| ▸ | CCR1 | P32246 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464540 | 0.97 | MCHR1 (0.59) | MCHR1CCR3CCR1SIGMAR1DRD2 | |
| SCHEMBL7461314 | 0.89 | MCHR1 (0.61) | MCHR1CCR3CCR1SIGMAR1DRD2 | |
| SCHEMBL7460992 | 0.89 | MCHR1 (0.60) | MCHR1CCR3CCR1SIGMAR1DRD2 | |
| SCHEMBL7464781 | 0.87 | MCHR1 (0.73) | MCHR1CCR3CCR1SIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL7466687 | 0.86 | MCHR1 (0.59) | MCHR1SIGMAR1DRD2 | |
| SCHEMBL7470937 | 0.85 | MCHR1 (0.58) | MCHR1SIGMAR1DRD2 | |
| SCHEMBL7462324 | 0.84 | MCHR1 (0.57) | MCHR1SIGMAR1DRD2 | |
| SCHEMBL7460592 | 0.84 | MCHR1 (0.62) | MCHR1CCR3CCR1SIGMAR1DRD2 | |
| SCHEMBL7466759 | 0.84 | MCHR1 (0.66) | MCHR1 | |
| SCHEMBL7470119 | 0.83 | MCHR1 (0.68) | MCHR1CCR3CCR1SIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |