Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603027 | 0.89 | SLC6A4 (0.51) | MTNR1AMTNR1BFFAR1 | |
| Oxalic Acid SCHEMBL7310180 | 0.80 | FFAR1 (0.52) | LMNAMTNR1AMTNR1BL3MBTL1FFAR1 | |
| SCHEMBL14063965 | 0.80 | SLC6A9 (0.54) | LMNAFFAR1 | |
| SCHEMBL7051306 | 0.79 | SLC6A4 (0.54) | LMNAMTNR1AMTNR1BL3MBTL1FFAR1 | |
| SCHEMBL1775169 | 0.79 | KMT2A (0.46) | MTNR1AMTNR1BL3MBTL1TACR1 | |
| SCHEMBL7310188 | 0.78 | LMNA (0.47) | LMNAMTNR1AMTNR1BL3MBTL1FFAR1 | |
| Oxalic Acid SCHEMBL7309554 | 0.78 | SLC6A9 (0.56) | — | |
| SCHEMBL4734665 | 0.77 | SLC6A4 (0.60) | — | |
| Butanone SCHEMBL4457167 | 0.77 | SLC6A4 (0.40) | LMNAMTNR1AMTNR1BL3MBTL1FFAR1 | |
| SCHEMBL7053900 | 0.77 | SLC6A4 (0.75) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040102-A4 | ARYLTHIAZOLIDINEDIONE DERIVATIVES | MERCK & CO INC (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-1194146-A4 | ARYLTHIAZOLIDINEDIONE AND ARYLOXAZOLIDINEDIONE DERIVATIVES | MERCK & CO INC (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-1194146-A1 | ARYLTHIAZOLIDINEDIONE AND ARYLOXAZOLIDINEDIONE DERIVATIVES | Merck & Co., Inc. (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078312-A1 | ARYLTHIAZOLIDINEDIONE AND ARYLOXAZOLIDINEDIONE DERIVATIVES | MERCK & CO., INC. (US) | 2000-12-28 | — | — | WO | disclosed |
| EP-1040102-A1 | ARYLTHIAZOLIDINEDIONE DERIVATIVES | Merck & Co., Inc. (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999032465-A1 | ARYLTHIAZOLIDINEDIONE DERIVATIVES | MERCK & CO., INC. (US) | 1999-07-01 | — | — | WO | disclosed |