Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6733533 | 1.00 | LMNA (0.52) | LMNAMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6737762 | 0.88 | ALDH1A1 (0.60) | LMNAMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6740425 | 0.84 | ALDH1A1 (0.58) | LMNAMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6739627 | 0.83 | LMNA (0.52) | LMNAMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6738120 | 0.83 | ALDH1A1 (0.54) | LMNAMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6735158 | 0.83 | ALDH1A1 (0.54) | LMNAMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6738470 | 0.83 | ALDH1A1 (0.54) | LMNAMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6740194 | 0.82 | ALDH1A1 (0.60) | LMNAMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6739641 | 0.82 | ALDH1A1 (0.60) | LMNAMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7846334 | 0.82 | ELANE (0.67) | LMNAMAPTALDH1A1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098894-B1 | FKBP INHIBITORS | PFIZER LTD (GB) | 2002-10-02 | — | — | EP | disclosed |