Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 10/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7470069 | 0.99 | CCR5 (0.52) | CCR5SIGMAR1OPRM1ACHEKCNH2 | |
| Hydrochloric Acid SCHEMBL7468181 | 0.88 | CCR5 (0.50) | CCR5ACHECYP2D6 | |
| SCHEMBL7455494 | 0.87 | CCR5 (0.49) | CCR5SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7465772 | 0.86 | CCR5 (0.70) | CCR5OPRM1 | |
| SCHEMBL7456202 | 0.86 | CCR5 (0.49) | CCR5SIGMAR1KCNH2 | |
| SCHEMBL7466072 | 0.85 | OPRD1 (0.48) | CCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL7460596 | 0.85 | CCR5 (0.58) | CCR5OPRM1ACHE | |
| Hydrochloric Acid SCHEMBL7455052 | 0.84 | CCR5 (0.52) | CCR5SIGMAR1OPRM1 | |
| SCHEMBL7463708 | 0.84 | HTT (0.48) | CCR5ACHE | |
| SCHEMBL7463510 | 0.84 | CCR5 (0.48) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180513-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-20 | — | — | EP | disclosed |