Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.44 |
| ▸ | AGXT | P21549 | 4/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468357 | 0.87 | AGXT (0.43) | MAOBAGXTIDO1NR4A2LMNA | |
| SCHEMBL7465277 | 0.86 | AGXT (0.41) | MAOBAGXTIDO1NR4A2LMNA | |
| SCHEMBL7459997 | 0.81 | MAOB (0.52) | MAOBAGXTIDO1NR4A2MRGPRX4 | |
| SCHEMBL1291660 | 0.81 | MAOB (0.50) | MAOBAGXTIDO1NR4A2LMNA | |
| SCHEMBL10743886 | 0.81 | MAOB (0.40) | MAOBNR4A2LMNAL3MBTL1PTGS1 | |
| SCHEMBL7464222 | 0.77 | FFAR1 (0.41) | MAOBAGXTIDO1LMNAFFAR1 | |
| SCHEMBL6098768 | 0.75 | TAAR1 (0.38) | MAOBFFAR1SRCMAOA | |
| SCHEMBL13723495 | 0.74 | SLC6A4 (0.47) | MAOBAGXTIDO1NR4A2MAOA | |
| SCHEMBL13723329 | 0.74 | MAOB (0.47) | MAOBAGXTIDO1MAOA | |
| SCHEMBL7460118 | 0.74 | MAOB (0.43) | MAOBAGXTIDO1NR4A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | disclosed |