Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468357 | 0.89 | AGXT (0.43) | AGXTMRGPRX4MGLLMAOBNR4A2 | |
| SCHEMBL7464303 | 0.86 | MAOB (0.44) | AGXTMRGPRX4MAOBNR4A2LMNA | |
| SCHEMBL7464222 | 0.85 | FFAR1 (0.41) | AGXTMAOBGSTP1ALDH1A1LMNA | |
| SCHEMBL14060231 | 0.81 | MAOB (0.43) | AGXTMAOBNR4A2IDO1MAOA | |
| SCHEMBL10743886 | 0.80 | MAOB (0.40) | MAOBNR4A2LMNAMAOA | |
| SCHEMBL2451731 | 0.78 | MAOB (0.43) | AGXTMAOBMAPTALDH1A1HPGD | |
| SCHEMBL7459997 | 0.75 | MAOB (0.52) | AGXTMRGPRX4MAOBNR4A2MAPT | |
| SCHEMBL3973667 | 0.74 | IDO1 (0.48) | AGXTGSTP1HPGDLMNAHTT | |
| SCHEMBL5621755 | 0.74 | RXRA (0.40) | MAPTALDH1A1HPGDLMNAPOLB | |
| SCHEMBL7460676 | 0.74 | KDM4E (0.49) | MAPTALDH1A1HPGDHTTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | disclosed |