Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619156 | 1.00 | LMNA (0.43) | LMNAMEN1KMT2ABCL2A1POLB | |
| Hydrochloric Acid SCHEMBL7454269 | 0.99 | LMNA (0.43) | LMNAMEN1KMT2ABCL2A1POLB | |
| SCHEMBL8086087 | 0.87 | POLB (0.47) | POLB | |
| SCHEMBL7619118 | 0.83 | EPHX1 (0.43) | KMT2AEPHX1DPP4 | |
| SCHEMBL7610382 | 0.83 | EPHX1 (0.43) | KMT2AEPHX1DPP4 | |
| SCHEMBL27965419 | 0.77 | CYP2D6 (0.37) | LMNAMEN1KMT2A | |
| SCHEMBL581121 | 0.77 | SMN1; SMN2 (0.42) | MEN1KMT2A | |
| SCHEMBL22861858 | 0.76 | HAT1 (0.52) | MEN1KMT2APOLB | |
| SCHEMBL28813336 | 0.76 | ALDH1A1 (0.42) | POLB | |
| SCHEMBL26210924 | 0.75 | LTA4H (0.40) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739892-B1 | Chromone derivatives | NOVARTIS AG (CH) | 2002-09-25 | — | — | EP | disclosed |
| EP-0783490-B1 | 1-ACYL-4-ALIPHATIC AMINOPIPERIDINE COMPOUNDS | NOVARTIS AG (CH) | 2002-02-06 | — | — | EP | disclosed |
| US-5604247-A | NEUROKININE ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-02-18 | — | — | US | disclosed |
| EP-0739892-A2 | Chromone derivatives | CIBA-GEIGY AG (CH) | 1996-10-30 | — | — | EP | disclosed |
| EP-0707006-A1 | Aroyl-piperidine derivatives | CIBA-GEIGY AG (CH) | 1996-04-17 | — | — | EP | disclosed |