Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455045 | 0.77 | HTT (0.44) | ALDH1A1POLBMAPTHPGDHSD17B10 | |
| SCHEMBL4908186 | 0.76 | CA12 (0.39) | ALDH1A1POLBMAPTMAPK1HPGD | |
| Urea SCHEMBL28254322 | 0.74 | ICAM1 (0.50) | ICAM1SELEALDH1A1POLBMAPT | |
| SCHEMBL28480606 | 0.74 | CA12 (0.59) | ALDH1A1POLBMAPTMAPK1HPGD | |
| SCHEMBL172361 | 0.74 | ACHE (0.39) | ALDH1A1MAPTMAPK1HPGDCA12 | |
| SCHEMBL14237961 | 0.74 | MAPT (0.45) | ALDH1A1POLBMAPTMAPK1HPGD | |
| SCHEMBL11688418 | 0.72 | RAB9A (0.40) | ALDH1A1POLBMAPTMAPK1HPGD | |
| SCHEMBL9824740 | 0.72 | IDO1 (0.46) | ALDH1A1MAPTHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL3643658 | 0.72 | SIRT1 (0.41) | ALDH1A1POLBMAPTHPGDHSD17B10 | |
| SCHEMBL14919249 | 0.72 | MAPT (0.41) | ICAM1SELEALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235826-A1 | QUINUCLIDINE ACRYLAMIDES | AstraZeneca AB (SE) | 2002-09-04 | — | — | EP | claimed |
| WO-2001029034-A1 | QUINUCLIDINE ACRYLAMIDES | ASTRAZENECA AB (SE) | 2001-04-26 | — | — | WO | claimed |