Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | KDM6B | O15054 | 1/20 | 0.56 |
| ▸ | KDM4A | O75164 | 1/20 | 0.56 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.56 |
| ▸ | ACLY | P53396 | 1/20 | 0.53 |
| ▸ | CDC7 | O00311 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688887 | 0.87 | ACLY (0.64) | MEN1KMT2AGRIK1L3MBTL1KDM4C | |
| SCHEMBL7467939 | 0.84 | GRIK1 (0.59) | GRIK1KDM4CKDM4EKDM6BKDM4A | |
| SCHEMBL1714812 | 0.83 | KDM4C (0.56) | MEN1KMT2AL3MBTL1KDM4CKDM4E | |
| SCHEMBL4980301 | 0.83 | KDR (0.64) | HDAC1KDRMAPK1 | |
| SCHEMBL15817727 | 0.80 | KDM4C (0.76) | KDM4CKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL1715089 | 0.79 | KDM4C (0.70) | MEN1KMT2AL3MBTL1KDM4CKDM4E | |
| SCHEMBL1714819 | 0.79 | KDM4C (0.85) | KDM4CKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL14389304 | 0.78 | ACLY (0.51) | MEN1KMT2AGRIK1KDM4EACLY | |
| SCHEMBL29855520 | 0.78 | ACLY (0.51) | MEN1KMT2AGRIK1KDM4EACLY | |
| SCHEMBL7461503 | 0.77 | HPGD (0.60) | MEN1KMT2AGRIK1KDM4EACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |