Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | KDM6B | O15054 | 1/20 | 0.58 |
| ▸ | KDM4A | O75164 | 1/20 | 0.58 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.55 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688887 | 0.85 | ACLY (0.64) | GRIK1KDM4CKDM4EKDM6BKDM4A | |
| SCHEMBL7464371 | 0.84 | MEN1 (0.59) | GRIK1KDM4CKDM4EKDM6BKDM4A | |
| SCHEMBL22071204 | 0.79 | KDM4C (0.53) | GRIK1KDM4CKDM4EKDM6BSMN1; SMN2 | |
| SCHEMBL10557452 | 0.78 | POLB (0.66) | KDM4EHTTLMNACDK5CDK5R1 | |
| SCHEMBL30611270 | 0.77 | GRIK1 (0.74) | GRIK1LMNAUSP2POLBALDH1A1 | |
| SCHEMBL29110322 | 0.77 | GRIK1 (0.74) | GRIK1LMNAUSP2POLBALDH1A1 | |
| SCHEMBL2382365 | 0.76 | USP2 (0.58) | KDM4CKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL913752 | 0.76 | CDK5 (0.62) | KDM4ECDK5CDK5R1SMN1; SMN2GAA | |
| SCHEMBL10556274 | 0.76 | ALDH1A1 (0.71) | KDM4EPOLBALDH1A1 | |
| SCHEMBL15817727 | 0.76 | KDM4C (0.76) | KDM4CKDM4EKDM6BKDM4AKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| US-5783698-A | REACTING HALOFORMATE FUNCTIONALIZED POLYSTYRENE WITH SUBSTITUTED ANTHRANILIC ACID DERIVATIVE TO FORM URETHANE LINKAGE, REACTING THE INTERMEDIATE WITH PRIMARY AMINE TO FORM ANTHRANILAMIDES, HEATING, CYCLIZATION, LIBERATING END PRODUCT | MERCK SHARP & DOHME LIMITED (GB) | 1998-07-21 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |