Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | DRD3 | P35462 | 5/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28747046 | 0.89 | ITGB3 (0.49) | CNR1CNR2DRD2DRD3ITGB3 | |
| SCHEMBL382962 | 0.89 | ITGB3 (0.49) | CNR1CNR2DRD2DRD3ITGB3 | |
| SCHEMBL6499974 | 0.85 | ITGB3 (0.43) | CNR1CNR2DRD2DRD3ITGB3 | |
| SCHEMBL6496378 | 0.84 | ITGB3 (0.42) | CNR1CNR2DRD2DRD3ITGB3 | |
| SCHEMBL382676 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2BGRIN3BGRIN1GRIN2C | |
| SCHEMBL6500046 | 0.83 | PRMT5 (0.44) | CNR1CNR2DRD2DRD3ITGB3 | |
| SCHEMBL7464438 | 0.83 | DRD2 (0.42) | CNR1CNR2DRD2DRD3ITGB3 | |
| SCHEMBL6499934 | 0.82 | ITGB3 (0.61) | ITGB3ITGA2BITGAV | |
| SCHEMBL6503934 | 0.82 | ITGB3 (0.42) | CNR1CNR2DRD2DRD3ITGB3 | |
| SCHEMBL382099 | 0.82 | ITGB3 (0.54) | DRD2DRD3ITGB3ITGA2BGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | claimed |
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | disclosed |