Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.42 |
| ▸ | DRD3 | P35462 | 6/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.38 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.38 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382964 | 0.89 | CASR (0.45) | DRD2DRD3HDAC1CASREPHX2 | |
| SCHEMBL6500015 | 0.86 | DRD2 (0.40) | DRD2DRD3CNR1CNR2HDAC1 | |
| SCHEMBL382678 | 0.84 | ITGB3 (0.44) | EPHX2ITGB3ITGAVITGA2B | |
| SCHEMBL7464402 | 0.83 | CNR1 (0.44) | DRD2DRD3CNR1CNR2HDAC1 | |
| SCHEMBL6499964 | 0.82 | KAT6A (0.43) | DRD2DRD3CNR1CNR2HDAC1 | |
| SCHEMBL382101 | 0.82 | ITGB3 (0.46) | DRD2DRD3CASRITGB3ITGAV | |
| SCHEMBL6501602 | 0.81 | KDM4E (0.56) | DRD2DRD3CNR1CNR2PLOD2 | |
| SCHEMBL7467089 | 0.81 | ITGB3 (0.43) | DRD2DRD3VCPITGB3ITGAV | |
| SCHEMBL6507021 | 0.80 | ITGB3 (0.41) | DRD2DRD3CNR1CNR2ITGB3 | |
| SCHEMBL6496356 | 0.80 | HDAC1 (0.41) | DRD2DRD3CNR1CNR2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | claimed |
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | disclosed |