Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | F7 | P08709 | 2/20 | 0.33 |
| ▸ | F3 | P13726 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471565 | 0.81 | HTT (0.42) | KDM4ELMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8308252 | 0.75 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL7470784 | 0.75 | CHRM2 (0.42) | TAAR1 | |
| SCHEMBL28028808 | 0.73 | KCNH2 (0.51) | SMN1; SMN2KDM4EKCNH2 | |
| SCHEMBL9073051 | 0.72 | TAAR1 (0.52) | MEN1KMT2ASMN1; SMN2KDM4EKCNH2 | |
| SCHEMBL7468749 | 0.72 | SIGMAR1 (0.47) | TP53KCNH2TAAR1MAPTALOX15 | |
| SCHEMBL6559348 | 0.72 | KCNH2 (0.49) | MEN1KMT2ASMN1; SMN2TP53KCNH2 | |
| SCHEMBL442769 | 0.72 | KCNH2 (0.49) | MEN1KMT2ASMN1; SMN2TP53KCNH2 | |
| SCHEMBL10494779 | 0.72 | KCNH2 (0.49) | MEN1KMT2ASMN1; SMN2TP53KCNH2 | |
| SCHEMBL10494813 | 0.72 | KCNH2 (0.49) | MEN1KMT2ASMN1; SMN2TP53KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | disclosed |