Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549527 | 0.96 | TSHR (0.43) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL20656 | 0.96 | TSHR (0.43) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Water SCHEMBL1155699 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Hydrogen Sulfide SCHEMBL9281216 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL809934 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Bromide SCHEMBL10582038 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Fluoride SCHEMBL635869 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL3429854 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL22204469 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 | |
| Fluoride SCHEMBL1264751 | 0.92 | TSHR (0.40) | TSHRALDH1A1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580650-A1 | NOVEL 2-SPIROCYCLOPROPYL 4-ACYLCEPHEMS AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES INC. (CA) | 1994-02-02 | — | — | EP | disclosed |
| US-5258377-A | Elastase inhibitors | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| WO-1992017482-A1 | NOVEL 2-SPIROCYCLOPROPYL 4-ACYLCEPHEMS AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES, INC. (CA) | 1992-10-15 | — | — | WO | disclosed |