Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 7/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.45 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473783 | 0.94 | FKBP1A (0.44) | FKBP1AABCC1FKBP4FKBP5PTAFR | |
| SCHEMBL7173479 | 0.72 | GFER (0.41) | FKBP1A | |
| SCHEMBL7173487 | 0.72 | GFER (0.41) | FKBP1A | |
| SCHEMBL7464560 | 0.71 | FKBP1A (0.42) | FKBP1AABCC1FKBP4FKBP5KDM4E | |
| SCHEMBL7177870 | 0.71 | FKBP1A (0.40) | FKBP1AABCC1FKBP4FKBP5ALDH1A1 | |
| SCHEMBL7177878 | 0.71 | FKBP1A (0.40) | FKBP1AABCC1FKBP4FKBP5ALDH1A1 | |
| SCHEMBL6570397 | 0.70 | KMT2A (0.42) | FKBP1AALDH1A1POLBHPGD | |
| SCHEMBL6570389 | 0.70 | KMT2A (0.42) | FKBP1AALDH1A1POLBHPGD | |
| SCHEMBL6573934 | 0.69 | L3MBTL1 (0.40) | FKBP1AKDM4EALDH1A1HPGD | |
| SCHEMBL6570407 | 0.69 | LPAR1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204657-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012622-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |