Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 6/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.43 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 5/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464552 | 0.94 | FKBP1A (0.47) | FKBP1AABCC1FKBP4FKBP5PTAFR | |
| SCHEMBL7176742 | 0.73 | CNR1 (0.38) | FKBP1AABCC1ALDH1A1 | |
| SCHEMBL7177956 | 0.73 | CNR1 (0.38) | FKBP1AABCC1ALDH1A1 | |
| SCHEMBL7473785 | 0.72 | CYP1A2 (0.37) | FKBP1AABCC1FKBP4FKBP5TBXAS1 | |
| Timcodar SCHEMBL30929684 | 0.71 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGD | |
| Timcodar SCHEMBL1492143 | 0.70 | L3MBTL1 (0.37) | FKBP1AALDH1A1 | |
| SCHEMBL6570451 | 0.70 | L3MBTL1 (0.37) | FKBP1AALDH1A1 | |
| Timcodar SCHEMBL3673444 | 0.70 | L3MBTL1 (0.37) | FKBP1AALDH1A1 | |
| SCHEMBL6570448 | 0.70 | L3MBTL1 (0.37) | FKBP1AALDH1A1 | |
| SCHEMBL7181772 | 0.70 | F10 (0.38) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204657-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012622-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |