Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650855 | 0.89 | GRIN1 (0.42) | GRIN1MEN1PKMKMT2A | |
| SCHEMBL7471711 | 0.87 | GRIN1 (0.39) | GRIN1ALDH1A1 | |
| SCHEMBL8488434 | 0.81 | GRIN1 (0.43) | GRIN1ALDH1A1MEN1PKMKMT2A | |
| SCHEMBL7470542 | 0.80 | GRIN1 (0.39) | GRIN1MEN1PKMKMT2A | |
| SCHEMBL8488354 | 0.79 | GRIN1 (0.40) | GRIN1ALDH1A1MEN1PKMKMT2A | |
| SCHEMBL8488133 | 0.76 | GRIN1 (0.39) | GRIN1ALDH1A1MEN1PKMKMT2A | |
| SCHEMBL8930335 | 0.75 | GRIN1 (0.38) | GRIN1 | |
| SCHEMBL8487399 | 0.74 | GRIN1 (0.40) | GRIN1MEN1PKMKMT2A | |
| SCHEMBL8488510 | 0.74 | GRIN1 (0.49) | GRIN1ALDH1A1MEN1PKMKMT2A | |
| SCHEMBL7467566 | 0.74 | GRIN1 (0.39) | GRIN1ALDH1A1MEN1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783495-B1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LTD (GB) | 2002-02-27 | — | — | EP | disclosed |
| US-5852016-A | Quinoxaline derivatives useful in therapy | PFIZER INC. (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0783495-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | Pfizer Limited (GB) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996009295-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LIMITED (GB) | 1996-03-28 | — | — | WO | disclosed |