Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 10/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470542 | 0.85 | GRIN1 (0.39) | GRIN1GLP1R | |
| SCHEMBL8650855 | 0.85 | GRIN1 (0.42) | GRIN1GLP1R | |
| SCHEMBL7472397 | 0.85 | GRIN1 (0.35) | GRIN1GLP1R | |
| SCHEMBL8524581 | 0.84 | MCL1 (0.34) | GRIN1 | |
| SCHEMBL7470510 | 0.81 | RAB9A (0.46) | GRIN1 | |
| SCHEMBL7476576 | 0.81 | GRIN1 (0.35) | GRIN1GLP1R | |
| SCHEMBL8490082 | 0.81 | GRIN1 (0.37) | GRIN1 | |
| SCHEMBL7467566 | 0.80 | GRIN1 (0.39) | GRIN1 | |
| SCHEMBL8488510 | 0.80 | GRIN1 (0.49) | GRIN1 | |
| SCHEMBL8930645 | 0.80 | GRIN1 (0.36) | GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031902-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-09-04 | — | — | WO | disclosed |
| EP-0792874-A1 | Quinoxaline derivatives useful in therapy | Pfizer Limited (GB) | 1997-09-03 | — | — | EP | disclosed |