Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465244 | 0.87 | F10 (0.43) | CMA1MAPTTP53MEN1KMT2A | |
| SCHEMBL7463810 | 0.86 | SMN1; SMN2 (0.45) | TP53MEN1KMT2AS1PR2PSEN1 | |
| SCHEMBL7472833 | 0.82 | MAPT (0.48) | CMA1MAPTTP53MEN1KMT2A | |
| SCHEMBL7468103 | 0.82 | GAA (0.44) | CMA1MAPTTP53MEN1KMT2A | |
| SCHEMBL7563746 | 0.80 | MAPT (0.49) | MAPTTP53MEN1KMT2AS1PR2 | |
| SCHEMBL7468006 | 0.79 | MAPT (0.46) | CMA1MAPTTP53MEN1KMT2A | |
| SCHEMBL7468043 | 0.79 | MAPT (0.48) | MAPTTP53MEN1KMT2APOLB | |
| SCHEMBL7463225 | 0.79 | CMA1 (0.42) | CMA1MAPTTP53S1PR2PSEN1 | |
| SCHEMBL7461911 | 0.79 | MAPT (0.44) | CMA1MAPTTP53MEN1KMT2A | |
| SCHEMBL7466453 | 0.78 | CMA1 (0.37) | CMA1MAPTTP53S1PR2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |