Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463810 | 0.88 | SMN1; SMN2 (0.45) | MEN1KMT2AS1PR2TP53PSEN1 | |
| SCHEMBL7468103 | 0.88 | GAA (0.44) | F10CMA1MEN1KMT2ATP53 | |
| SCHEMBL7464635 | 0.87 | CMA1 (0.37) | CMA1MEN1KMT2AS1PR2POLB | |
| SCHEMBL7472833 | 0.85 | MAPT (0.48) | CMA1MEN1KMT2APOLBTP53 | |
| SCHEMBL7468043 | 0.83 | MAPT (0.48) | NLRP3MEN1KMT2APOLBTP53 | |
| SCHEMBL7563746 | 0.82 | MAPT (0.49) | MEN1KMT2AS1PR2POLBTP53 | |
| SCHEMBL7468006 | 0.81 | MAPT (0.46) | CMA1MEN1KMT2AS1PR2POLB | |
| SCHEMBL7463225 | 0.81 | CMA1 (0.42) | CMA1S1PR2TP53MAPTPSEN1 | |
| SCHEMBL7470111 | 0.80 | ALDH1A1 (0.50) | MEN1KMT2AS1PR2TP53MAPT | |
| SCHEMBL7465177 | 0.80 | S1PR2 (0.49) | CMA1MEN1KMT2AS1PR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |