Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | CCR3 | P51677 | 10/20 | 0.47 |
| ▸ | CCR1 | P32246 | 7/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7465064 | 0.99 | MCHR1 (0.52) | MCHR1CCR3CCR1DRD2ADRB2 | |
| SCHEMBL7462064 | 0.97 | MCHR1 (0.54) | MCHR1CCR3CCR1KCNA3MEN1 | |
| Hydrochloric Acid SCHEMBL7458878 | 0.96 | MCHR1 (0.54) | MCHR1CCR3CCR1KCNA3CX3CR1 | |
| SCHEMBL7463216 | 0.92 | MCHR1 (0.60) | MCHR1DRD2KCNA3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7469999 | 0.91 | MCHR1 (0.59) | MCHR1DRD2KCNA3MEN1KMT2A | |
| SCHEMBL7464873 | 0.88 | MCHR1 (0.56) | MCHR1CCR3CCR1DRD2KCNA3 | |
| SCHEMBL7466786 | 0.84 | MCHR1 (0.54) | MCHR1CCR3CCR1DRD2KCNA3 | |
| Hydrochloric Acid SCHEMBL7464242 | 0.83 | MCHR1 (0.54) | MCHR1CCR3CCR1DRD2KCNA3 | |
| SCHEMBL7459803 | 0.82 | CHRM4 (0.50) | CCR3CCR1DRD2KCNA3 | |
| Hydrochloric Acid SCHEMBL8869803 | 0.81 | CHRM4 (0.52) | CCR3CCR1DRD2KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |