Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7464242 | 0.99 | MCHR1 (0.54) | MCHR1SIGMAR1DRD2OPRM1CCR1 | |
| SCHEMBL7463216 | 0.91 | MCHR1 (0.60) | MCHR1SIGMAR1DRD2KCNA3 | |
| Hydrochloric Acid SCHEMBL7469999 | 0.90 | MCHR1 (0.59) | MCHR1SIGMAR1DRD2KCNA3 | |
| SCHEMBL7462064 | 0.87 | MCHR1 (0.54) | MCHR1SIGMAR1CCR1CCR3KCNA3 | |
| SCHEMBL7464873 | 0.87 | MCHR1 (0.56) | MCHR1SIGMAR1DRD2CCR1CCR3 | |
| Hydrochloric Acid SCHEMBL7458878 | 0.86 | MCHR1 (0.54) | MCHR1SIGMAR1CCR1CCR3KCNA3 | |
| SCHEMBL7460786 | 0.85 | DRD2 (0.52) | MCHR1SIGMAR1DRD2OPRM1CCR1 | |
| SCHEMBL7464640 | 0.84 | MCHR1 (0.53) | MCHR1DRD2CCR1CCR3KCNA3 | |
| Hydrochloric Acid SCHEMBL7465064 | 0.83 | MCHR1 (0.52) | MCHR1DRD2CCR1CCR3KCNA3 | |
| SCHEMBL7462124 | 0.80 | CCR1 (0.67) | CCR1CCR3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |