Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 5/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463216 | 0.96 | MCHR1 (0.60) | MCHR1KCNA3SIGMAR1MEN1TP53 | |
| Hydrochloric Acid SCHEMBL7469999 | 0.95 | MCHR1 (0.59) | MCHR1KCNA3SIGMAR1MEN1TP53 | |
| SCHEMBL7462064 | 0.90 | MCHR1 (0.54) | MCHR1KCNA3SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7458878 | 0.89 | MCHR1 (0.54) | MCHR1KCNA3SIGMAR1MEN1KMT2A | |
| SCHEMBL7464640 | 0.88 | MCHR1 (0.53) | MCHR1KCNA3MEN1KMT2ACCR1 | |
| SCHEMBL7461929 | 0.88 | SIGMAR1 (0.57) | MCHR1KCNA3SIGMAR1MEN1TP53 | |
| Hydrochloric Acid SCHEMBL7465064 | 0.88 | MCHR1 (0.52) | MCHR1KCNA3MEN1KMT2ACCR1 | |
| SCHEMBL7466786 | 0.87 | MCHR1 (0.54) | MCHR1KCNA3SIGMAR1CCR1CCR3 | |
| Hydrochloric Acid SCHEMBL7464242 | 0.86 | MCHR1 (0.54) | MCHR1KCNA3SIGMAR1CCR1CCR3 | |
| SCHEMBL7526133 | 0.81 | KCNA3 (0.72) | KCNA3CCR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |