Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 3/20 | 0.46 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.41 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474097 | 0.91 | HRH4 (0.56) | HRH4HTR6HTTCDK1EIF2AK2 | |
| SCHEMBL7473166 | 0.91 | HTR6 (0.55) | HRH4HTR6HTTEIF2AK2ALDH1A1 | |
| SCHEMBL7465055 | 0.91 | HTR6 (0.55) | HRH4HTR6HTTCDK1EIF2AK2 | |
| SCHEMBL7470693 | 0.90 | HTT (0.45) | HRH4HTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL7469384 | 0.89 | HTT (0.46) | HTR6HTTCDK1ALDH1A1MAPT | |
| SCHEMBL7470361 | 0.88 | HTT (0.45) | HRH4HTTCDK1SMN1; SMN2PIK3CA | |
| SCHEMBL7469367 | 0.86 | MAPT (0.44) | HTR6HTTCDK1ALDH1A1MAPT | |
| SCHEMBL7471389 | 0.84 | MAPT (0.41) | HTR6HTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7476281 | 0.83 | HRH4 (0.51) | HRH4HTR6HTTCDK1EIF2AK2 | |
| SCHEMBL7470182 | 0.82 | HTT (0.50) | HRH4HTTALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |