Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.41 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.41 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470182 | 0.91 | HTT (0.50) | HRH4HTTNR2F2CNR1CNR2 | |
| SCHEMBL7464890 | 0.91 | HRH4 (0.48) | HRH4HTTHTR6CDK1WDR5 | |
| SCHEMBL7465055 | 0.91 | HTR6 (0.55) | HRH4HTTHTR3AHTR6CDK1 | |
| SCHEMBL7463152 | 0.90 | HTT (0.48) | HRH4HTTNR2F2CDK1CNR1 | |
| SCHEMBL7466405 | 0.90 | HTT (0.48) | HRH4HTTNR2F2CNR1CNR2 | |
| SCHEMBL7470593 | 0.90 | HTT (0.50) | HRH4HTTHTR3ANR2F2CNR1 | |
| SCHEMBL7471116 | 0.89 | HTT (0.52) | HRH4HTTHTR6NR2F2CNR1 | |
| SCHEMBL7470615 | 0.88 | HTT (0.50) | HRH4HTTNR2F2CDK1CNR1 | |
| SCHEMBL7469787 | 0.86 | HTT (0.48) | HRH4HTTNR2F2CNR1CNR2 | |
| SCHEMBL7466801 | 0.86 | HTT (0.48) | HRH4HTTHTR6NR2F2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |