Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
| ▸ | FNTA | P49354 | 19/20 | 0.46 |
| ▸ | FNTB | P49356 | 19/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 15/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7927442 | 0.98 | FNTA (0.46) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7939463 | 0.86 | KCNH2 (0.38) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7937509 | 0.80 | FNTA (0.69) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| Hydrochloric Acid SCHEMBL7939633 | 0.79 | FNTA (0.68) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| Hydrochloric Acid SCHEMBL7939637 | 0.79 | FNTA (0.68) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL8298317 | 0.78 | BRS3 (0.48) | — | |
| SCHEMBL7464954 | 0.77 | FNTA (0.45) | KCNH2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8304229 | 0.77 | BRS3 (0.47) | — | |
| SCHEMBL7936234 | 0.76 | FNTA (0.64) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL7689560 | 0.73 | FNTA (0.59) | KCNH2FNTAFNTBPGGT1BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |