Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 16/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455892 | 0.95 | MCHR1 (0.43) | MCHR1PYGLDRD3CYP51A1 | |
| SCHEMBL7458988 | 0.95 | MCHR1 (0.48) | MCHR1PYGLDRD3CYP51A1 | |
| SCHEMBL7459200 | 0.93 | MCHR1 (0.45) | MCHR1DRD3 | |
| SCHEMBL7460453 | 0.92 | CCR1 (0.44) | MCHR1PYGLDRD3CYP51A1 | |
| SCHEMBL7466835 | 0.91 | MCHR1 (0.45) | MCHR1DRD3 | |
| SCHEMBL7468710 | 0.91 | CACNA1G (0.43) | MCHR1PYGLDRD3 | |
| SCHEMBL7465013 | 0.90 | MCHR1 (0.53) | MCHR1PYGLDRD3 | |
| SCHEMBL7466978 | 0.90 | KDM4E (0.46) | MCHR1DRD3 | |
| SCHEMBL7460484 | 0.88 | CACNA1G (0.43) | MCHR1PYGLDRD3 | |
| SCHEMBL7465649 | 0.87 | MCHR1 (0.46) | MCHR1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |