Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 15/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239865 | 0.89 | CA1 (0.59) | CA1CA2CA9PTGS2PTGS1 | |
| SCHEMBL3863035 | 0.88 | CA1 (0.81) | CA1CA2CA9PTGS2PTGS1 | |
| SCHEMBL3872673 | 0.88 | CA1 (0.64) | CA1CA2CA9PTGS2PTGS1 | |
| SCHEMBL9209865 | 0.86 | PTGS2 (0.67) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7872946 | 0.84 | PTGS2 (0.62) | CA1CA2CA9PTGS2PTGS1 | |
| SCHEMBL9297089 | 0.84 | PTGS2 (0.65) | CA1CA2CA9PTGS2PTGS1 | |
| SCHEMBL8421888 | 0.83 | PTGS2 (0.71) | CA1CA2CA9PTGS2PTGS1 | |
| SCHEMBL7468149 | 0.82 | PTGS2 (0.66) | CA1CA2CA9PTGS2PTGS1 | |
| SCHEMBL3867032 | 0.81 | CA1 (0.61) | CA1CA2CA9PTGS2PTGS1 | |
| SCHEMBL7465814 | 0.81 | CA1 (0.52) | CA1CA2CA9PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554829-B1 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-05-15 | — | — | EP | disclosed |
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0554829-A2 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |