Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27525604 | 0.86 | SLC7A5 (0.56) | SLC7A5ADRB2ADRB1ADRB3KLK5 | |
| SCHEMBL22442929 | 0.82 | ADRB2 (0.40) | SLC7A5ADRB2ADRB1ADRB3KLK5 | |
| SCHEMBL30759366 | 0.82 | ITGA4 (0.51) | SLC7A5KLK5ITGA4ITGB7CTSS | |
| SCHEMBL487422 | 0.82 | ITGA4 (0.51) | SLC7A5KLK5ITGA4ITGB7CTSS | |
| SCHEMBL487423 | 0.82 | ITGA4 (0.51) | SLC7A5KLK5ITGA4ITGB7CTSS | |
| SCHEMBL7470063 | 0.81 | SLC7A5 (0.46) | SLC7A5ADRB2ADRB1ADRB3KLK5 | |
| SCHEMBL31689508 | 0.80 | CTSS (0.54) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL3073448 | 0.77 | CTSS (0.47) | SLC7A5ADRB2KLK5CTSSCTSK | |
| SCHEMBL755879 | 0.77 | KDM6B (0.54) | SLC7A5ADRB2MAOAMAOBCPN1 | |
| SCHEMBL6680700 | 0.77 | KLK5 (0.61) | KLK5CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |