Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470386 | 0.84 | CACNA1B (0.38) | KDM1A | |
| SCHEMBL7457773 | 0.83 | CHRM2 (0.35) | CHRM1CHRM3CHRM2OPRL1CKS1B | |
| SCHEMBL9435372 | 0.80 | ALDH1A1 (0.38) | MEN1CYP1A2CYP2D6KMT2AHTT | |
| SCHEMBL7467853 | 0.80 | MAPT (0.38) | KDM1A | |
| SCHEMBL5774548 | 0.76 | ALDH1A1 (0.43) | MEN1TSHRNFKB1KMT2A | |
| SCHEMBL2457519 | 0.65 | KDM1A (0.39) | CHRM1CHRM3CHRM2OPRL1CKS1B | |
| SCHEMBL7668439 | 0.65 | ALDH1A1 (0.33) | MEN1ALOX15KMT2AHTT | |
| SCHEMBL1671830 | 0.65 | — | — | |
| SCHEMBL28600497 | 0.62 | KDM4C (0.45) | OPRL1CKS1BSKP1SKP2NFKB1 | |
| SCHEMBL931643 | 0.62 | MBTD1 (0.57) | CKS1BSKP1SKP2HTR3EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |