Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27266272 | 0.98 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2POLBGAAMAPT | |
| SCHEMBL27885327 | 0.92 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2POLBHPGDNPSR1 | |
| SCHEMBL28288019 | 0.90 | TSHR (0.36) | ALDH1A1SMN1; SMN2POLBGAAMAPT | |
| SCHEMBL5774548 | 0.83 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2POLBMAPTLMNA | |
| SCHEMBL27735180 | 0.83 | SIGMAR1 (0.41) | ALDH1A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL7465154 | 0.80 | CHRM1 (0.38) | MEN1KMT2ACYP1A2CYP2D6HTT | |
| SCHEMBL27544631 | 0.72 | HPGD (0.41) | ALDH1A1SMN1; SMN2POLBHPGDMEN1 | |
| SCHEMBL7668439 | 0.71 | ALDH1A1 (0.33) | ALDH1A1HPGDNPSR1MEN1KMT2A | |
| SCHEMBL28205818 | 0.71 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBMAPTHPGD | |
| SCHEMBL1933552 | 0.70 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2POLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283362-A | Reacting with an amine, terminating the reaction before the formation of by-product | CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) | 1994-02-01 | — | — | US | disclosed |