Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2802608 | 0.83 | PDE4D (0.56) | PPARGPPARDPPARAHTR1AEPHX2 | |
| SCHEMBL27107627 | 0.83 | NR1I2 (0.50) | PPARGPPARDPPARALMNAMAPK1 | |
| SCHEMBL9836311 | 0.81 | PPARG (0.51) | PPARGPPARDPPARALMNATDP1 | |
| SCHEMBL12898700 | 0.81 | SLC2A1 (0.54) | PPARGPPARDPPARALMNAMAPK1 | |
| SCHEMBL22210842 | 0.81 | PDE4D (0.45) | PPARGPPARDPPARALMNAMAPK1 | |
| SCHEMBL19389236 | 0.81 | NR1I2 (0.48) | PPARGPPARDPPARALMNAMAPK1 | |
| SCHEMBL7187157 | 0.81 | PPARG (0.45) | PPARGPPARDPPARALMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL10440707 | 0.80 | SLC2A1 (0.56) | PPARGPPARDPPARALMNAMAPK1 | |
| SCHEMBL7517519 | 0.79 | SLC2A1 (0.46) | — | |
| SCHEMBL7521457 | 0.78 | MTNR1A (0.44) | EPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | disclosed |