Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 7/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.44 |
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470616 | 0.83 | GPR84 (0.40) | SLC2A1MMP13MMP9ADAM17MMP1 | |
| SCHEMBL25620267 | 0.82 | SLC2A1 (0.49) | SLC2A1MMP13MMP9ADAM17MMP1 | |
| SCHEMBL3217271 | 0.82 | SLC2A1 (0.49) | SLC2A1MMP13MMP9ADAM17MMP1 | |
| SCHEMBL25620259 | 0.82 | SLC2A1 (0.49) | SLC2A1MMP13MMP9ADAM17MMP1 | |
| SCHEMBL25620258 | 0.82 | SLC2A1 (0.49) | SLC2A1MMP13MMP9ADAM17MMP1 | |
| SCHEMBL25620266 | 0.82 | SLC2A1 (0.49) | SLC2A1MMP13MMP9ADAM17MMP1 | |
| SCHEMBL25620261 | 0.82 | SLC2A1 (0.49) | SLC2A1MMP13MMP9ADAM17MMP1 | |
| SCHEMBL7521457 | 0.82 | MTNR1A (0.44) | — | |
| SCHEMBL10327515 | 0.81 | AOC3 (0.53) | SLC2A1MMP13MMP9ADAM17MMP1 | |
| SCHEMBL28584500 | 0.81 | SLC2A1 (0.47) | SLC2A1MMP13MMP9ADAM17MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | disclosed |